Phosphoproteome profiling uncovers a key role for CDKs in TNF signaling

Tumor necrosis factor (TNF) is one of the few cytokines successfully targeted by therapies against inflammatory diseases. However, blocking this well studied and pleiotropic ligand can cause dramatic side-effects. Here, we reason that a systems-level proteomic analysis of TNF signaling could dissect...

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Detalles Bibliográficos
Autores principales: Tanzer, Maria C., Bludau, Isabell, Stafford, Che A., Hornung, Veit, Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523534/
https://www.ncbi.nlm.nih.gov/pubmed/34663829
http://dx.doi.org/10.1038/s41467-021-26289-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523534/
https://www.ncbi.nlm.nih.gov/pubmed/34663829
http://dx.doi.org/10.1038/s41467-021-26289-6

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