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Dysregulation of T(FH)-B-T(RM) lymphocyte cooperation is associated with unfavorable anti-PD-1 responses in EGFR-mutant lung cancer

Patients with non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutations exhibit an unfavorable response to PD-1 inhibitor through unclear mechanisms. Hypothesizing that EGFR mutations alter tumor-immune interactions, we compare tumor-infiltrating lymphocytes between E...

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Detalles Bibliográficos
Autores principales: Cho, Jae-Won, Park, Seyeon, Kim, Gamin, Han, Heonjong, Shim, Hyo Sup, Shin, Sunhye, Bae, Yong-Soo, Park, Seong Yong, Ha, Sang-Jun, Lee, Insuk, Kim, Hye Ryun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523541/
https://www.ncbi.nlm.nih.gov/pubmed/34663810
http://dx.doi.org/10.1038/s41467-021-26362-0