Rosmarinic acid inhibits DNA glycation and modulates the expression of Akt1 and Akt3 partially in the hippocampus of diabetic rats

Non-enzymatic glycation of DNA and the associated effects are among pathogenic factors in diabetes mellitus. Natural polyphenols have anti-diabetic activity. Herein, the protective role of one of the phytochemicals, rosmarinic acid (RA), was evaluated in glycation (with fructose) of human DNA and ex...

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Detalles Bibliográficos
Autores principales: Alrubaye, Ameer, Motovali-Bashi, Majid, Miroliaei, Mehran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523555/
https://www.ncbi.nlm.nih.gov/pubmed/34663861
http://dx.doi.org/10.1038/s41598-021-99286-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523555/
https://www.ncbi.nlm.nih.gov/pubmed/34663861
http://dx.doi.org/10.1038/s41598-021-99286-w

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