Arabidopsis thaliana PrimPol is a primase and lesion bypass DNA polymerase with the biochemical characteristics to cope with DNA damage in the nucleus, mitochondria, and chloroplast

PrimPol is a novel Primase–Polymerase that synthesizes RNA and DNA primers de novo and extents from these primers as a DNA polymerase. Animal PrimPol is involved in nuclear and mitochondrial DNA replication by virtue of its translesion DNA synthesis (TLS) and repriming activities. Here we report tha...

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Detalles Bibliográficos
Autores principales: García-Medel, Paola L., Peralta-Castro, Antolín, Baruch-Torres, Noe, Fuentes-Pascacio, Alma, Pedroza-García, José A., Cruz-Ramirez, Alfredo, Brieba, Luis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523556/
https://www.ncbi.nlm.nih.gov/pubmed/34663822
http://dx.doi.org/10.1038/s41598-021-00151-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523556/
https://www.ncbi.nlm.nih.gov/pubmed/34663822
http://dx.doi.org/10.1038/s41598-021-00151-7

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