Deregulation of hsa_circ_0001971/miR-186 and hsa_circ_0001874/miR-296 signaling pathways promotes the proliferation of oral squamous carcinoma cells by synergistically activating SHP2/PLK1 signals

It has been demonstrated that circ_0001874 and circ_0001971 are potential biomarkers for the diagnosis of oral squamous carcinoma (OSCC). MiR-186 was reported to serve as a tumor suppressor in OSCC, and the down-regulation of miR-186 was reported to lead to higher expression of oncogenic factor SHP2...

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Detalles Bibliográficos
Autores principales: Jun, Wang, Shaobo, Ouyang, Xianhua, Zhang, Siyu, Zhao, Mingyang, Cheng, Xin, Fan, Ying, Cai, Lan, Liao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523700/
https://www.ncbi.nlm.nih.gov/pubmed/34663837
http://dx.doi.org/10.1038/s41598-021-99488-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523700/
https://www.ncbi.nlm.nih.gov/pubmed/34663837
http://dx.doi.org/10.1038/s41598-021-99488-2

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