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Deregulation of hsa_circ_0001971/miR-186 and hsa_circ_0001874/miR-296 signaling pathways promotes the proliferation of oral squamous carcinoma cells by synergistically activating SHP2/PLK1 signals
It has been demonstrated that circ_0001874 and circ_0001971 are potential biomarkers for the diagnosis of oral squamous carcinoma (OSCC). MiR-186 was reported to serve as a tumor suppressor in OSCC, and the down-regulation of miR-186 was reported to lead to higher expression of oncogenic factor SHP2...
Autores principales: | Jun, Wang, Shaobo, Ouyang, Xianhua, Zhang, Siyu, Zhao, Mingyang, Cheng, Xin, Fan, Ying, Cai, Lan, Liao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523700/ https://www.ncbi.nlm.nih.gov/pubmed/34663837 http://dx.doi.org/10.1038/s41598-021-99488-2 |
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