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Connecting MHC-I-binding motifs with HLA alleles via deep learning

The selection of peptides presented by MHC molecules is crucial for antigen discovery. Previously, several predictors have shown impressive performance on binding affinity. However, the decisive MHC residues and their relation to the selection of binding peptides are still unrevealed. Here, we conne...

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Detalles Bibliográficos
Autores principales: Lee, Ko-Han, Chang, Yu-Chuan, Chen, Ting-Fu, Juan, Hsueh-Fen, Tsai, Huai-Kuang, Chen, Chien-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523706/
https://www.ncbi.nlm.nih.gov/pubmed/34663927
http://dx.doi.org/10.1038/s42003-021-02716-8