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Connecting MHC-I-binding motifs with HLA alleles via deep learning
The selection of peptides presented by MHC molecules is crucial for antigen discovery. Previously, several predictors have shown impressive performance on binding affinity. However, the decisive MHC residues and their relation to the selection of binding peptides are still unrevealed. Here, we conne...
Autores principales: | Lee, Ko-Han, Chang, Yu-Chuan, Chen, Ting-Fu, Juan, Hsueh-Fen, Tsai, Huai-Kuang, Chen, Chien-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523706/ https://www.ncbi.nlm.nih.gov/pubmed/34663927 http://dx.doi.org/10.1038/s42003-021-02716-8 |
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