The presynaptic glycine transporter GlyT2 is regulated by the Hedgehog pathway in vitro and in vivo

The identity of a glycinergic synapse is maintained presynaptically by the activity of a surface glycine transporter, GlyT2, which recaptures glycine back to presynaptic terminals to preserve vesicular glycine content. GlyT2 loss-of-function mutations cause Hyperekplexia, a rare neurological disease...

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Detalles Bibliográficos
Autores principales: de la Rocha-Muñoz, Andrés, Núñez, Enrique, Vishwanath, Anjali Amrapali, Gómez-López, Sergio, Dhanasobhon, Dhanasak, Rebola, Nelson, López-Corcuera, Beatriz, de Juan-Sanz, Jaime, Aragón, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523746/
https://www.ncbi.nlm.nih.gov/pubmed/34663888
http://dx.doi.org/10.1038/s42003-021-02718-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523746/
https://www.ncbi.nlm.nih.gov/pubmed/34663888
http://dx.doi.org/10.1038/s42003-021-02718-6

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