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The presynaptic glycine transporter GlyT2 is regulated by the Hedgehog pathway in vitro and in vivo
The identity of a glycinergic synapse is maintained presynaptically by the activity of a surface glycine transporter, GlyT2, which recaptures glycine back to presynaptic terminals to preserve vesicular glycine content. GlyT2 loss-of-function mutations cause Hyperekplexia, a rare neurological disease...
Autores principales: | de la Rocha-Muñoz, Andrés, Núñez, Enrique, Vishwanath, Anjali Amrapali, Gómez-López, Sergio, Dhanasobhon, Dhanasak, Rebola, Nelson, López-Corcuera, Beatriz, de Juan-Sanz, Jaime, Aragón, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523746/ https://www.ncbi.nlm.nih.gov/pubmed/34663888 http://dx.doi.org/10.1038/s42003-021-02718-6 |
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