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Signaling Pathways in Proton and Non-proton ASIC1a Activation

Acid-sensing ion channels (ASICs) regulate synaptic activities and play important roles in neurodegenerative diseases as well as pain conditions. Classically, ASICs are described as transiently activated by a reduced pH, followed by desensitization; the activation allows sodium influx, and in the ca...

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Detalles Bibliográficos
Autores principales: Salinas Castellanos, Libia Catalina, Uchitel, Osvaldo Daniel, Weissmann, Carina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523820/
https://www.ncbi.nlm.nih.gov/pubmed/34675777
http://dx.doi.org/10.3389/fncel.2021.735414