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Biofunctional magnesium-coated Ti6Al4V scaffolds promote autophagy-dependent apoptosis in osteosarcoma by activating the AMPK/mTOR/ULK1 signaling pathway

The recurrence of osteosarcoma (OS) after reconstruction using Ti6Al4V prostheses remains a major problem in the surgical treatment of OS. Modification of the surfaces of Ti6Al4V prostheses with antitumor functions is an important strategy for improving therapeutic outcomes. Magnesium (Mg) coating h...

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Detalles Bibliográficos
Autores principales: Wei, X., Tang, Z., Wu, H., Zuo, X., Dong, H., Tan, L., Wang, W., Liu, Y., Wu, Z., Shi, L., Wang, N., Li, X., Xiao, X., Guo, Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523865/
https://www.ncbi.nlm.nih.gov/pubmed/34704011
http://dx.doi.org/10.1016/j.mtbio.2021.100147