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Biofunctional magnesium-coated Ti6Al4V scaffolds promote autophagy-dependent apoptosis in osteosarcoma by activating the AMPK/mTOR/ULK1 signaling pathway
The recurrence of osteosarcoma (OS) after reconstruction using Ti6Al4V prostheses remains a major problem in the surgical treatment of OS. Modification of the surfaces of Ti6Al4V prostheses with antitumor functions is an important strategy for improving therapeutic outcomes. Magnesium (Mg) coating h...
Autores principales: | Wei, X., Tang, Z., Wu, H., Zuo, X., Dong, H., Tan, L., Wang, W., Liu, Y., Wu, Z., Shi, L., Wang, N., Li, X., Xiao, X., Guo, Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523865/ https://www.ncbi.nlm.nih.gov/pubmed/34704011 http://dx.doi.org/10.1016/j.mtbio.2021.100147 |
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