LGR5-Positive Supporting Cells Survive Ototoxic Trauma in the Adult Mouse Cochlea

Sensorineural hearing loss is mainly caused by irreversible damage to sensory hair cells (HCs). A subgroup of supporting cells (SCs) in the cochlea express leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5), a marker for tissue-resident stem cells. LGR5+ SCs could be used as an endog...

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Detalles Bibliográficos
Autores principales: Smith-Cortinez, Natalia, Yadak, Rana, Hendriksen, Ferry G. J., Sanders, Eefje, Ramekers, Dyan, Stokroos, Robert J., Versnel, Huib, Straatman, Louise V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523910/
https://www.ncbi.nlm.nih.gov/pubmed/34675775
http://dx.doi.org/10.3389/fnmol.2021.729625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523910/
https://www.ncbi.nlm.nih.gov/pubmed/34675775
http://dx.doi.org/10.3389/fnmol.2021.729625

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