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The Role of IL-36 in the Pathophysiological Processes of Autoimmune Diseases

A member of the interleukin (IL)-1 superfamily was IL-36, which contained IL-36α, IL-36β, IL-36γ, and IL-36Ra. Heterotrimer complexes, consisting of heterodimeric receptor complexes and IL-36 agonist, gave signals through intracellular functional domains, so as to bind to downstream proteins and ind...

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Detalles Bibliográficos
Autores principales: Chen, Wen-jian, Yu, Xiao, Yuan, Xin-Rong, Chen, Bang-jie, Cai, Na, Zeng, Shuo, Sun, Yuan-song, Li, Hai-wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523922/
https://www.ncbi.nlm.nih.gov/pubmed/34675805
http://dx.doi.org/10.3389/fphar.2021.727956