The Partitioning of Newly Assimilated Linoleic and α-Linolenic Acids Between Synthesis of Longer-Chain Polyunsaturated Fatty Acids and Hydroxyoctadecaenoic Acids Is a Putative Branch Point in T-Cell Essential Fatty Acid Metabolism

Longer-chain polyunsaturated fatty acids (LCPUFAs) ≥20 carbons long are required for leukocyte function. These can be obtained from the diet, but there is some evidence that leukocytes can convert essential fatty acids (EFAs) into LCPUFAs. We used stable isotope tracers to investigate LCPUFA biosynt...

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Detalles Bibliográficos
Autores principales: von Gerichten, Johanna, West, Annette L., Irvine, Nicola A., Miles, Elizabeth A., Calder, Philip C., Lillycrop, Karen A., Fielding, Barbara A., Burdge, Graham C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523940/
https://www.ncbi.nlm.nih.gov/pubmed/34675928
http://dx.doi.org/10.3389/fimmu.2021.740749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523940/
https://www.ncbi.nlm.nih.gov/pubmed/34675928
http://dx.doi.org/10.3389/fimmu.2021.740749

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