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Germacrone Attenuates Hepatic Stellate Cells Activation and Liver Fibrosis via Regulating Multiple Signaling Pathways

Liver fibrosis is an abnormal proliferation of connective tissue in the liver caused by various pathogenic factors. Chronic liver injury leads to release of inflammatory cytokines and reactive oxygen species (ROS) from damaged hepatocytes, which activates hepatic stellate cells (HSCs) to secrete ext...

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Detalles Bibliográficos
Autores principales: Li, Zhiyong, Wang, Zhilei, Dong, Fang, Shi, Wei, Dai, Wenzhang, Zhao, Jing, Li, Qiang, Fang, Zhi-e, Ren, Lutong, Liu, Tingting, Wei, Ziying, Mou, Wenqing, Lin, Li, Yang, Yan, Xiao, Xiaohe, Ma, Li, Bai, Zhaofang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523941/
https://www.ncbi.nlm.nih.gov/pubmed/34675811
http://dx.doi.org/10.3389/fphar.2021.745561