Pan-cancer Analysis of Tumor Mutational Burden and Homologous Recombination DNA Damage Repair Using Targeted Next-Generation Sequencing

PURPOSE: Current variability in methods for tumor mutational burden (TMB) estimation and reporting demonstrates the urgent need for a homogeneous TMB assessment approach. Here, we compared TMB distributions in different cancer types using two customized targeted panels commonly used in clinical prac...

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Detalles Bibliográficos
Autores principales: Wang, Hai-Yun, Deng, Ling, Li, Ying-Qing, Zhang, Xiao, Long, Ya-Kang, Zhang, Xu, Feng, Yan-Fen, He, Yuan, Tang, Tao, Yang, Xin-Hua, Wang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524032/
https://www.ncbi.nlm.nih.gov/pubmed/33677848
http://dx.doi.org/10.4143/crt.2020.798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524032/
https://www.ncbi.nlm.nih.gov/pubmed/33677848
http://dx.doi.org/10.4143/crt.2020.798

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