Suppression of Transmembrane Tumor Necrosis Factor Alpha Processing by a Specific Antibody Protects Against Colitis-Associated Cancer

Soluble tumor necrosis factor-α (sTNF-α) plays an important role in colitis-associated cancer (CAC); however, little is known about transmembrane TNF-α (tmTNF-α). Here, we observed an increase in sTNF-α mainly in colitis tissues from an azoxymethane/dextran sodium sulfate (DSS)-induced CAC mouse mod...

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Detalles Bibliográficos
Autores principales: Ba, Hongping, Jiang, Rui, Zhang, Meng, Yin, Bingjiao, Wang, Jing, Li, Zhuoya, Li, Baihua, Zhou, Xiaoxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524043/
https://www.ncbi.nlm.nih.gov/pubmed/34675913
http://dx.doi.org/10.3389/fimmu.2021.687874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524043/
https://www.ncbi.nlm.nih.gov/pubmed/34675913
http://dx.doi.org/10.3389/fimmu.2021.687874

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