Cargando…

Suppression of Transmembrane Tumor Necrosis Factor Alpha Processing by a Specific Antibody Protects Against Colitis-Associated Cancer

Soluble tumor necrosis factor-α (sTNF-α) plays an important role in colitis-associated cancer (CAC); however, little is known about transmembrane TNF-α (tmTNF-α). Here, we observed an increase in sTNF-α mainly in colitis tissues from an azoxymethane/dextran sodium sulfate (DSS)-induced CAC mouse mod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ba, Hongping, Jiang, Rui, Zhang, Meng, Yin, Bingjiao, Wang, Jing, Li, Zhuoya, Li, Baihua, Zhou, Xiaoxi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524043/ https://www.ncbi.nlm.nih.gov/pubmed/34675913 http://dx.doi.org/10.3389/fimmu.2021.687874

Ejemplares similares

Antitumor effect of CAR-T cells targeting transmembrane tumor necrosis factor alpha combined with PD-1 mAb on breast cancers
por: Ba, Hongping, et al.
Publicado: (2023)

Inhibition of transmembrane TNF-α shedding by a specific antibody protects against septic shock
por: Li, Chenxi, et al.
Publicado: (2019)

Transmembrane tumor necrosis factor alpha attenuates pressure-overload cardiac hypertrophy via tumor necrosis factor receptor 2
por: Miao, Kun, et al.
Publicado: (2020)

Transmembrane TNF-alpha promotes chemoresistance in breast cancer cells
por: Zhang, Zunyue, et al.
Publicado: (2018)

Forward and Reverse Signaling Mediated by Transmembrane Tumor Necrosis Factor-Alpha and TNF Receptor 2: Potential Roles in an Immunosuppressive Tumor Microenvironment
por: Qu, Yang, et al.
Publicado: (2017)

Suppression Colitis and Colitis-Associated Colon Cancer by Anti-S100a9 Antibody in Mice
por: Zhang, Xuemei, et al.
Publicado: (2017)

Tumor Necrosis Factor-Alpha Targeting Can Protect against Arthritis with Low Sensitization to Infection
por: Belmellat, Nadia, et al.
Publicado: (2017)

Transmembrane Tumor Necrosis Factor Controls Myeloid-Derived Suppressor Cell Activity via TNF Receptor 2 and Protects from Excessive Inflammation during BCG-Induced Pleurisy
por: Chavez-Galan, Leslie, et al.
Publicado: (2017)

A native-like bispecific antibody suppresses the inflammatory cytokine response by simultaneously neutralizing tumor necrosis factor-alpha and interleukin-17A
por: Xu, Tianshu, et al.
Publicado: (2017)

Role of Eosinophils and Tumor Necrosis Factor Alpha in Interleukin-25-Mediated Protection from Amebic Colitis
por: Noor, Zannatun, et al.
Publicado: (2017)

Juglone Suppresses Inflammation and Oxidative Stress in Colitis Mice
por: Chen, Shuai, et al.
Publicado: (2021)

Suppression of microRNA-222-3p ameliorates ulcerative colitis and colitis-associated colorectal cancer to protect against oxidative stress via targeting BRG1 to activate Nrf2/HO-1 signaling pathway
por: Wang, Xue-jun, et al.
Publicado: (2023)

Peroxisome Proliferator-Activated Receptor Alpha Mediates the Beneficial Effects of Atorvastatin in Experimental Colitis
por: Basso, Paulo José, et al.
Publicado: (2021)

IP-10 Promotes Blood–Brain Barrier Damage by Inducing Tumor Necrosis Factor Alpha Production in Japanese Encephalitis
por: Wang, Ke, et al.
Publicado: (2018)

Leptin Mediates In Vivo Neutrophil Migration: Involvement of Tumor Necrosis Factor-Alpha and CXCL1
por: Souza-Almeida, Glaucia, et al.
Publicado: (2018)

Role of tumor necrosis factor-alpha in the central nervous system: a focus on autoimmune disorders
por: Gonzalez Caldito, Natalia
Publicado: (2023)

T cell lymphoproliferative disorders associated with anti-tumor necrosis factor alpha antibody therapy for ulcerative colitis: literature summary
por: Schmidt, Lindsay A., et al.
Publicado: (2009)

Interleukin-4 Programmed Macrophages Suppress Colitis and Do Not Enhance Infectious-Colitis, Inflammation-Associated Colon Cancer or Airway Hypersensitivity
por: Callejas, Blanca E., et al.
Publicado: (2021)

Independent Associations of Tumor Necrosis Factor-Alpha and Interleukin-1 Beta With Radiographic Emphysema in People Living With HIV
por: Thudium, Rebekka F., et al.
Publicado: (2021)

Basic characterization of antibodies targeting receptors of the tumor necrosis factor receptor superfamily
por: Zaitseva, Olena, et al.
Publicado: (2023)

The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection
por: Li, Chang, et al.
Publicado: (2018)

Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis
por: Meiners, Jana, et al.
Publicado: (2019)

Plasmacytoid Dendritic Cells Provide Protection Against Bacterial-Induced Colitis
por: Rahman, Tania, et al.
Publicado: (2019)

Soluble SIRP-Alpha Promotes Murine Acute Lung Injury Through Suppressing Macrophage Phagocytosis
por: Shen, Qinjun, et al.
Publicado: (2022)

Roles of macrophages on ulcerative colitis and colitis-associated colorectal cancer
por: Zhang, Maorun, et al.
Publicado: (2023)

Genetic and Functional Associations with Decreased Anti-inflammatory Tumor Necrosis Factor Alpha Induced Protein 3 in Macrophages from Subjects with Axial Spondyloarthritis
por: Liu, Yiping, et al.
Publicado: (2017)

Tumor necrosis factor-alpha blockade suppresses BK polyomavirus replication
por: Li, Yi-Jung, et al.
Publicado: (2022)

Critical Role of Alternative M2 Skewing in miR-155 Deletion-Mediated Protection of Colitis
por: Li, Jintao, et al.
Publicado: (2018)

Immune Protection of a Helminth Protein in the DSS-Induced Colitis Model in Mice
por: Long, Shao Rong, et al.
Publicado: (2021)

Protective role of colitis in inflammatory arthritis via propionate-producing Bacteroides in the gut
por: Shon, Hoh-Jeong, et al.
Publicado: (2023)

Positive Regulation of the Antiviral Activity of Interferon-Induced Transmembrane Protein 3 by S-Palmitoylation
por: Wen, Shubo, et al.
Publicado: (2022)

Tumor Necrosis Factor-Alpha Antagonist Interferes With the Formation of Granulomatous Multinucleated Giant Cells: New Insights Into Mycobacterium tuberculosis Infection
por: Mezouar, Soraya, et al.
Publicado: (2019)

Tofacitinib Ameliorates Lupus Through Suppression of T Cell Activation Mediated by TGF-Beta Type I Receptor
por: Yan, Qing, et al.
Publicado: (2021)

Autophagy Enhancing Contributes to the Organ Protective Effect of Alpha-Lipoic Acid in Septic Rats
por: Jia, Jia, et al.
Publicado: (2019)

Canine Interferon-Inducible Transmembrane Protein Is a Host Restriction Factor That Potently Inhibits Replication of Emerging Canine Influenza Virus
por: Lu, Gang, et al.
Publicado: (2021)

The Immune Change of the Lung and Bowel in an Ulcerative Colitis Rat Model and the Protective Effect of Sodium Houttuyfonate Combined With Matrine
por: Ni, Lulu, et al.
Publicado: (2022)

Corrigendum: Critical Role of Alternative M2 Skewing in miR-155 Deletion-Mediated Protection of Colitis
por: Li, Jintao, et al.
Publicado: (2020)

Anti-High Mobility Group Box 1 Neutralizing-Antibody Ameliorates Dextran Sodium Sulfate Colitis in Mice
por: Chen, Liping, et al.
Publicado: (2020)

The Dynamics of Interleukin-10-Afforded Protection during Dextran Sulfate Sodium-Induced Colitis
por: Cardoso, Ana, et al.
Publicado: (2018)

The CD28 Transmembrane Domain Contains an Essential Dimerization Motif
por: Leddon, Scott A., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_efbuspeb1r9j1ogdnpg55lijaj