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A Substituted Diphenyl Amide Based Novel Scaffold Inhibits Staphylococcus aureus Virulence in a Galleria mellonella Infection Model

Antimicrobial compounds can combat microbes through modulating host immune defense, inhibiting bacteria survival and growth, or through impeding or inhibiting virulence factors. In the present study, a panel of substituted diphenyl amide compounds previously found to disrupt bacterial quorum sensing...

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Detalles Bibliográficos
Autores principales: Mishra, Biswajit, Khader, Rajamohammed, Felix, Lewis Oscar, Frate, Marissa, Mylonakis, Eleftherios, Meschwitz, Susan, Fuchs, Beth Burgwyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524085/
https://www.ncbi.nlm.nih.gov/pubmed/34675898
http://dx.doi.org/10.3389/fmicb.2021.723133