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HES1 protein oscillations are necessary for neural stem cells to exit from quiescence

Quiescence is a dynamic process of reversible cell cycle arrest. High-level persistent expression of the HES1 transcriptional repressor, which oscillates with an ultradian periodicity in proliferative neural stem cells (NSCs), is thought to mediate quiescence. However, it is not known whether this i...

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Detalles Bibliográficos
Autores principales: Marinopoulou, Elli, Biga, Veronica, Sabherwal, Nitin, Miller, Anzy, Desai, Jayni, Adamson, Antony D., Papalopulu, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524149/
https://www.ncbi.nlm.nih.gov/pubmed/34703994
http://dx.doi.org/10.1016/j.isci.2021.103198