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A stochastic model of homeostasis: The roles of noise and nuclear positioning in deciding cell fate

We study a population-based cellular model that starts from a single stem cell that divides stochastically to give rise to either daughter stem cells or differentiated daughter cells. There are three main components in the model: nucleus position, the underlying gene-regulatory network, and stochast...

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Detalles Bibliográficos
Autores principales: Jangid, Amit, Selvarajan, Suriya, Ramaswamy, Ram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524154/
https://www.ncbi.nlm.nih.gov/pubmed/34703995
http://dx.doi.org/10.1016/j.isci.2021.103199