GluN2B S1303 phosphorylation by CaMKII or DAPK1: no indication for involvement in ischemia or LTP

Binding of two different CaM kinases, CaMKII and DAPK1, to the NMDA-type glutamate receptor (NMDAR) subunit GluN2B near S1303 has been implicated in excitotoxic/ischemic neuronal cell death. The GluN2B(ΔCaMKII) mutation (L1298A, R1300Q) is neuroprotective but abolishes only CaMKII but not DAPK1 bind...

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Detalles Bibliográficos
Autores principales: Tullis, Jonathan E., Buonarati, Olivia R., Coultrap, Steven J., Bourke, Ashley M., Tiemeier, Erika L., Kennedy, Matthew J., Herson, Paco S., Bayer, K. Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524186/
https://www.ncbi.nlm.nih.gov/pubmed/34704002
http://dx.doi.org/10.1016/j.isci.2021.103214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524186/
https://www.ncbi.nlm.nih.gov/pubmed/34704002
http://dx.doi.org/10.1016/j.isci.2021.103214

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