Downregulation of matriptase suppresses the PAR-2/PLCγ2/PKC-mediated invasion and migration abilities of MCF-7 breast cancer cells

Matriptases, members of the type II transmembrane serine protease family, are cell surface proteolytic enzymes that mediate tumor invasion and metastasis. Matriptase is highly expressed in breast cancer and is associated with poor patient outcome. However, the cellular mechanism by which matriptase...

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Detalles Bibliográficos
Autores principales: Kim, Jeong-Mi, Park, Jinny, Noh, Eun-Mi, Song, Hyun-Kyung, Kang, Sang Yull, Jung, Sung Hoo, Kim, Jong-Suk, Youn, Hyun Jo, Lee, Young-Rae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524316/
https://www.ncbi.nlm.nih.gov/pubmed/34608498
http://dx.doi.org/10.3892/or.2021.8198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524316/
https://www.ncbi.nlm.nih.gov/pubmed/34608498
http://dx.doi.org/10.3892/or.2021.8198

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