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Downregulation of matriptase suppresses the PAR-2/PLCγ2/PKC-mediated invasion and migration abilities of MCF-7 breast cancer cells
Matriptases, members of the type II transmembrane serine protease family, are cell surface proteolytic enzymes that mediate tumor invasion and metastasis. Matriptase is highly expressed in breast cancer and is associated with poor patient outcome. However, the cellular mechanism by which matriptase...
Autores principales: | Kim, Jeong-Mi, Park, Jinny, Noh, Eun-Mi, Song, Hyun-Kyung, Kang, Sang Yull, Jung, Sung Hoo, Kim, Jong-Suk, Youn, Hyun Jo, Lee, Young-Rae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524316/ https://www.ncbi.nlm.nih.gov/pubmed/34608498 http://dx.doi.org/10.3892/or.2021.8198 |
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