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Trained Innate Immunity Induced by Vaccination with Low-Virulence Candida Species Mediates Protection against Several Forms of Fungal Sepsis via Ly6G(+) Gr-1(+) Leukocytes

We recently discovered a novel form of trained innate immunity (TII) induced by low-virulence Candida species (i.e., Candida dubliniensis) that protects against lethal fungal/bacterial infection. Mice vaccinated by intraperitoneal (i.p.) inoculation are protected against lethal sepsis following Cand...

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Detalles Bibliográficos
Autores principales: Lilly, Elizabeth A., Bender, Breah E., Esher Righi, Shannon, Fidel, Paul L., Noverr, Mairi C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524338/
https://www.ncbi.nlm.nih.gov/pubmed/34663098
http://dx.doi.org/10.1128/mBio.02548-21