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Adenylyl Cyclase and Protein Kinase A Play Redundant and Distinct Roles in Growth, Differentiation, Antifungal Drug Resistance, and Pathogenicity of Candida auris

Candida auris is a globally emerging multidrug-resistant fungal pathogen. Its pathogenicity-related signaling networks are largely unknown. Here, we characterized the pathobiological functions of the cyclic AMP (cAMP)/protein kinase A (PKA) signaling pathway in C. auris. We focused on adenylyl cycla...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Seok, Lee, Kyung-Tae, Lee, Myung Ha, Cheong, Eunji, Bahn, Yong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524339/
https://www.ncbi.nlm.nih.gov/pubmed/34663094
http://dx.doi.org/10.1128/mBio.02729-21