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NEP1-40 promotes myelin regeneration via upregulation of GAP-43 and MAP-2 expression after focal cerebral ischemia in rats

Axon regeneration after lesions to the central nervous system (CNS) is largely limited by the presence of growth inhibitory molecules expressed in myelin. Nogo-A is a principal inhibitor of neurite outgrowth, and blocking the activity of Nogo-A can induce axonal sprouting and functional recovery. Ho...

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Detalles Bibliográficos
Autores principales: Zhao, Hong, Liu, Zhen-Dong, Zhang, Yong-Bo, Gao, Xiao-Yu, Wang, Cui, Liu, Yi, Wang, Xun-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524407/
https://www.ncbi.nlm.nih.gov/pubmed/34643252
http://dx.doi.org/10.3892/mmr.2021.12484