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NEP1-40 promotes myelin regeneration via upregulation of GAP-43 and MAP-2 expression after focal cerebral ischemia in rats
Axon regeneration after lesions to the central nervous system (CNS) is largely limited by the presence of growth inhibitory molecules expressed in myelin. Nogo-A is a principal inhibitor of neurite outgrowth, and blocking the activity of Nogo-A can induce axonal sprouting and functional recovery. Ho...
Autores principales: | Zhao, Hong, Liu, Zhen-Dong, Zhang, Yong-Bo, Gao, Xiao-Yu, Wang, Cui, Liu, Yi, Wang, Xun-Fen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524407/ https://www.ncbi.nlm.nih.gov/pubmed/34643252 http://dx.doi.org/10.3892/mmr.2021.12484 |
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