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Protective multi-target effects of DL-3-n-butylphthalide combined with 3-methyl-1-phenyl-2-pyrazolin-5-one in mice with ischemic stroke

DL-3-n-butylphthalide (NBP) and 3-methyl-1- phenyl-2-pyrazolin-5-one (edaravone) are acknowledged neuroprotective agents that protect against ischemic stroke. However, the underlying mechanisms of a combination therapy with NBP and edaravone have not yet been fully clarified. The aim of the present...

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Detalles Bibliográficos
Autores principales: Guan, Yali, Li, Pengfei, Liu, Yingshuo, Guo, Lan, Wu, Qingwen, Cheng, Yuefa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524408/
https://www.ncbi.nlm.nih.gov/pubmed/34643246
http://dx.doi.org/10.3892/mmr.2021.12490