Interrupted Curtius Rearrangements of Quaternary Proline Derivatives: A Flow Route to Acyclic Ketones and Unsaturated Pyrrolidines

[Image: see text] Conversion of N-Boc-protected quaternary proline derivatives under thermal Curtius rearrangement conditions was found to afford a series of ring-opened ketone and unsaturated pyrrolidine products instead of the expected carbamate species. The nature of the substituent on the quater...

Descripción completa

Detalles Bibliográficos
Autores principales: Baumann, Marcus, Moody, Thomas S., Smyth, Megan, Wharry, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524412/
https://www.ncbi.nlm.nih.gov/pubmed/34170701
http://dx.doi.org/10.1021/acs.joc.1c01133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524412/
https://www.ncbi.nlm.nih.gov/pubmed/34170701
http://dx.doi.org/10.1021/acs.joc.1c01133

Ejemplares similares