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Gram-Scale Domino Synthesis in Batch and Flow Mode of Azetidinium Salts

[Image: see text] Azetidinium salts are important motifs in organic synthesis but are difficult to obtain due to extremely long synthetic protocols. Herein, a rapid continuous-flow process for the on-demand synthesis of azetidinium salts is described. In particular, the nucleophilic addition of seco...

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Detalles Bibliográficos
Autores principales: Sivo, Alessandra, Ruta, Vincenzo, Vilé, Gianvito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524416/
https://www.ncbi.nlm.nih.gov/pubmed/34469143
http://dx.doi.org/10.1021/acs.joc.1c01487