Continuous Flow Synthesis of α-Trifluoromethylthiolated Esters and Amides from Carboxylic Acids: a Telescoped Approach

[Image: see text] A continuous flow approach to access α-trifluoromethylthiolated esters and amides using commercially available arylacetic acids and N-(trifluoromethylthio)phthalimide as the electrophilic reagent is described. The experimental protocol involves the in-flow conversion of the carboxy...

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Detalles Bibliográficos
Autores principales: Franco, Francesca, Meninno, Sara, Lattanzi, Alessandra, Puglisi, Alessandra, Benaglia, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524418/
https://www.ncbi.nlm.nih.gov/pubmed/34314582
http://dx.doi.org/10.1021/acs.joc.1c01270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524418/
https://www.ncbi.nlm.nih.gov/pubmed/34314582
http://dx.doi.org/10.1021/acs.joc.1c01270

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