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Functional Expression and Characterization of the Highly Promiscuous Lanthipeptide Synthetase SyncM, Enabling the Production of Lanthipeptides with a Broad Range of Ring Topologies

[Image: see text] Lanthipeptides are ribosomally synthesized and post-translationally modified peptides characterized by the presence of lanthionine rings that provide stability and functionality. Genome mining techniques have shown their huge diversity and potential for the discovery of novel activ...

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Detalles Bibliográficos
Autores principales: Arias-Orozco, Patricia, Inklaar, Maartje, Lanooij, Judith, Cebrián, Rubén, Kuipers, Oscar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524650/
https://www.ncbi.nlm.nih.gov/pubmed/34554737
http://dx.doi.org/10.1021/acssynbio.1c00224