β-naphthoflavone-induced upregulation of CYP1B1 expression is mediated by the preferential binding of aryl hydrocarbon receptor to unmethylated xenobiotic responsive elements

Human cytochrome P450 1 (CYP1) enzymes are transcriptionally induced by specific xenobiotics through a mechanism that involves the binding of aryl hydrocarbon receptors (AhR) to target xenobiotic responsive element (XRE) sequences. To examine the effect of DNA methylation on the AhR-mediated pathway...

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Detalles Bibliográficos
Autores principales: Miura, Toshitaka, Onodera, Ryo, Terashima, Jun, Ozawa, Shogo, Habano, Wataru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524661/
https://www.ncbi.nlm.nih.gov/pubmed/34676003
http://dx.doi.org/10.3892/etm.2021.10846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524661/
https://www.ncbi.nlm.nih.gov/pubmed/34676003
http://dx.doi.org/10.3892/etm.2021.10846

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