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Desialylation of platelet surface glycans enhances platelet adhesion to adsorbent polymers for lipoprotein apheresis

BACKGROUND: Lipoprotein apheresis is an important therapeutic option in homozygous familial hypercholesterolemia, progressive atherosclerosis, or when depletion of lipoprotein(a) is indicated. It is generally regarded as safe, but drops in platelet counts as well as sporadic episodes of thrombocytop...

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Detalles Bibliográficos
Autores principales: Lauková, Lucia, Weiss, René, Semak, Vladislav, Weber, Viktoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524686/
https://www.ncbi.nlm.nih.gov/pubmed/33143534
http://dx.doi.org/10.1177/0391398820968849