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Targeting PPARα in low ambient temperature exposure-induced cardiac dysfunction and remodeling
The present study demonstrates that the down-regulation of peroxisome proliferator-activated receptor-α (PPARα) results in chronic low ambient temperature (LT) exposure-induced cardiac dysfunction and remodeling, emphasizing the therapeutic potential of PPARα activation strategies (e.g. fenofibrate...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524846/ https://www.ncbi.nlm.nih.gov/pubmed/34663467 http://dx.doi.org/10.1186/s40779-021-00347-y |