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Hsp90 up-regulates PD-L1 to promote HPV-positive cervical cancer via HER2/PI3K/AKT pathway

BACKGROUND: HPV16 is the predominant cancer-causing strain that is responsible for over 50% of all cervical cancers. In this study, we aim to investigate the therapeutic effect of heat shock protein 90 (Hsp90) knockdown on HPV16(+) cervical cancer progression and the underlying mechanism. METHODS: T...

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Detalles Bibliográficos
Autores principales: Zeng, Jie, He, Si-Li, Li, Li-Jie, Wang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524852/
https://www.ncbi.nlm.nih.gov/pubmed/34666670
http://dx.doi.org/10.1186/s10020-021-00384-2