Cargando…
Hsp90 up-regulates PD-L1 to promote HPV-positive cervical cancer via HER2/PI3K/AKT pathway
BACKGROUND: HPV16 is the predominant cancer-causing strain that is responsible for over 50% of all cervical cancers. In this study, we aim to investigate the therapeutic effect of heat shock protein 90 (Hsp90) knockdown on HPV16(+) cervical cancer progression and the underlying mechanism. METHODS: T...
Autores principales: | Zeng, Jie, He, Si-Li, Li, Li-Jie, Wang, Chen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524852/ https://www.ncbi.nlm.nih.gov/pubmed/34666670 http://dx.doi.org/10.1186/s10020-021-00384-2 |
Ejemplares similares
-
Extracellular HSP90α Interacts With ER Stress to Promote Fibroblasts Activation Through PI3K/AKT Pathway in Pulmonary Fibrosis
por: Zhang, Jinming, et al.
Publicado: (2021) -
Baicalin Targets HSP70/90 to Regulate PKR/PI3K/AKT/eNOS Signaling Pathways
por: Hou, Yinzhu, et al.
Publicado: (2022) -
Heat Shock Protein 90 (HSP90) and Her2 in Adenocarcinomas of the Esophagus
por: Slotta-Huspenina, Julia, et al.
Publicado: (2014) -
Aspirin Enhances the Protection of Hsp90 from Heat-Stressed Injury in Cardiac Microvascular Endothelial Cells Through PI3K-Akt and PKM2 Pathways
por: Zhang, Xiaohui, et al.
Publicado: (2020) -
Aberrant HSP90 Expression in Lymphocytes and HSP90 Response to Anti-PD-1 Therapy in Lymphoma Patients
por: Albakova, Zarema, et al.
Publicado: (2022)