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Long noncoding RNA MAPKAPK5-AS1 promoted lipopolysaccharide-induced inflammatory damage in the myocardium by sponging microRNA-124-3p/E2F3

BACKGROUND: Myocardial dysfunction caused by sepsis (SIMD) leads to high mortality in critically ill patients. We investigated the function and mechanism of long non-coding RNA MAPKAPK5-AS1 (lncRNA MAPKAPK-AS1) on lipopolysaccharide (LPS)-induced inflammation response in vivo and in vitro. METHOD: M...

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Detalles Bibliográficos
Autores principales: Chen, Weiwei, Gao, Guangyuan, Yan, Mengjie, Yu, Ming, Shi, Kaiyao, Yang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524853/
https://www.ncbi.nlm.nih.gov/pubmed/34666672
http://dx.doi.org/10.1186/s10020-021-00385-1