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Cell competition between wild-type and JAK2V617F mutant cells prevents disease relapse after stem cell transplantation in a murine model of myeloproliferative neoplasm

Disease relapse after allogeneic stem cell transplantation is a major cause of treatment-related morbidity and mortality in patients with myeloproliferative neoplasms (MPNs). The cellular and molecular mechanisms for MPN relapse are not well understood. Here, we established a murine model of MPN rel...

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Detalles Bibliográficos
Autores principales: Zhang, Haotian, Castiglione, Melissa, Zheng, Lei, Zhan, Huichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524893/
https://www.ncbi.nlm.nih.gov/pubmed/34666822
http://dx.doi.org/10.1186/s40164-021-00241-2