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Cell competition between wild-type and JAK2V617F mutant cells prevents disease relapse after stem cell transplantation in a murine model of myeloproliferative neoplasm
Disease relapse after allogeneic stem cell transplantation is a major cause of treatment-related morbidity and mortality in patients with myeloproliferative neoplasms (MPNs). The cellular and molecular mechanisms for MPN relapse are not well understood. Here, we established a murine model of MPN rel...
Autores principales: | Zhang, Haotian, Castiglione, Melissa, Zheng, Lei, Zhan, Huichun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524893/ https://www.ncbi.nlm.nih.gov/pubmed/34666822 http://dx.doi.org/10.1186/s40164-021-00241-2 |
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