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Protein kinase C regulates organic anion transporter 1 through phosphorylating ubiquitin ligase Nedd4–2
BACKGROUND: Organic anion transporter 1 (OAT1) is a drug transporter expressed on the basolateral membrane of the proximal tubule cells in kidneys. It plays an essential role in the disposition of numerous clinical therapeutics, impacting their pharmacological and toxicological properties. The activ...
Autores principales: | Yu, Zhou, Liu, Chenchang, Zhang, Jinghui, Liang, Zhengxuan, You, Guofeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524912/ https://www.ncbi.nlm.nih.gov/pubmed/34663225 http://dx.doi.org/10.1186/s12860-021-00393-3 |
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