Comprehensive multi-omics integration identifies differentially active enhancers during human brain development with clinical relevance

BACKGROUND: Non-coding regulatory elements (NCREs), such as enhancers, play a crucial role in gene regulation, and genetic aberrations in NCREs can lead to human disease, including brain disorders. The human brain is a complex organ that is susceptible to numerous disorders; many of these are caused...

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Detalles Bibliográficos
Autores principales: Yousefi, Soheil, Deng, Ruizhi, Lanko, Kristina, Salsench, Eva Medico, Nikoncuk, Anita, van der Linde, Herma C., Perenthaler, Elena, van Ham, Tjakko J., Mulugeta, Eskeatnaf, Barakat, Tahsin Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524963/
https://www.ncbi.nlm.nih.gov/pubmed/34663447
http://dx.doi.org/10.1186/s13073-021-00980-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524963/
https://www.ncbi.nlm.nih.gov/pubmed/34663447
http://dx.doi.org/10.1186/s13073-021-00980-1

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