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Comprehensive multi-omics integration identifies differentially active enhancers during human brain development with clinical relevance
BACKGROUND: Non-coding regulatory elements (NCREs), such as enhancers, play a crucial role in gene regulation, and genetic aberrations in NCREs can lead to human disease, including brain disorders. The human brain is a complex organ that is susceptible to numerous disorders; many of these are caused...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524963/ https://www.ncbi.nlm.nih.gov/pubmed/34663447 http://dx.doi.org/10.1186/s13073-021-00980-1 |