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DNA methylation-calling tools for Oxford Nanopore sequencing: a survey and human epigenome-wide evaluation
BACKGROUND: Nanopore long-read sequencing technology greatly expands the capacity of long-range, single-molecule DNA-modification detection. A growing number of analytical tools have been developed to detect DNA methylation from nanopore sequencing reads. Here, we assess the performance of different...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524990/ https://www.ncbi.nlm.nih.gov/pubmed/34663425 http://dx.doi.org/10.1186/s13059-021-02510-z |