DNA methylation-calling tools for Oxford Nanopore sequencing: a survey and human epigenome-wide evaluation

BACKGROUND: Nanopore long-read sequencing technology greatly expands the capacity of long-range, single-molecule DNA-modification detection. A growing number of analytical tools have been developed to detect DNA methylation from nanopore sequencing reads. Here, we assess the performance of different...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Rosikiewicz, Wojciech, Pan, Ziwei, Jillette, Nathaniel, Wang, Ping, Taghbalout, Aziz, Foox, Jonathan, Mason, Christopher, Carroll, Martin, Cheng, Albert, Li, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524990/
https://www.ncbi.nlm.nih.gov/pubmed/34663425
http://dx.doi.org/10.1186/s13059-021-02510-z

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