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Recent Approaches for Manipulating Globin Gene Expression in Treating Hemoglobinopathies

Tissue oxygenation throughout life depends on the activity of hemoglobin (Hb) one of the hemeproteins that binds oxygen in the lungs and secures its delivery throughout the body. Hb is composed of four monomers encoded by eight different genes the expression of which is tightly regulated during deve...

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Detalles Bibliográficos
Autores principales: Mussolino, Claudio, Strouboulis, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525358/
https://www.ncbi.nlm.nih.gov/pubmed/34713248
http://dx.doi.org/10.3389/fgeed.2021.618111