Gene Editing of Hematopoietic Stem Cells: Hopes and Hurdles Toward Clinical Translation

In the field of hematology, gene therapies based on integrating vectors have reached outstanding results for a number of human diseases. With the advent of novel programmable nucleases, such as CRISPR/Cas9, it has been possible to expand the applications of gene therapy beyond semi-random gene addit...

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Detalles Bibliográficos
Autores principales: Ferrari, Samuele, Vavassori, Valentina, Canarutto, Daniele, Jacob, Aurelien, Castiello, Maria Carmina, Javed, Attya Omer, Genovese, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genome Editing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525369/
https://www.ncbi.nlm.nih.gov/pubmed/34713250
http://dx.doi.org/10.3389/fgeed.2021.618378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525369/
https://www.ncbi.nlm.nih.gov/pubmed/34713250
http://dx.doi.org/10.3389/fgeed.2021.618378

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